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Agenesis of the Corpus Callosum Therapy Options at NAPA

Jul 02nd, 2023 | by Kate Alexander

Kate Alexander

July 02nd, 2023

What is Agenesis of the Corpus Callosum?

Agenesis of the corpus callosum (ACC) is a rare, congenital (present at birth) brain defect which occurs when a structure called the corpus callosum does not develop normally, resulting in partial or complete absence. The corpus callosum is a band of tissue that connects the two hemispheres (sides of the brain), allowing the two sides to communicate. ACC is frequently diagnosed during the first 2 years of life.

What is the Cause of Agenesis of the Corpus Callosum?

The cause of ACC is not usually known, but can be inherited as an autosomal recessive trait (child inherits one mutated copy of a gene from each parent), or as an X-linked dominant trait (child inherits one mutated copy of the gene on a single X chromosome). It can also be caused by an infection or injury during the second trimester of pregnancy.

What Are Some Characteristics in Children With Agenesis of the Corpus Callosum?

The severity of the symptoms is dependent on the extent to which the corpus callosum is missing, and whether there are any other structural issues with the brain.

What Are Some Treatment Options for Agenesis of the Corpus Callosum?

Whilst there is no cure for ACC, early intervention through multidisciplinary treatment is recommended to support the development of gross motor, fine motor, feeding, communication, and cognitive skills. Physiotherapy may focus on increasing muscle strength, coordination and balance. Occupational therapy may target upper limb strength, hand-eye coordination, and functional upper limb use to support activities of daily living such as dressing. Speech and language pathology may address receptive and expressive language, and may also support feeding difficulties.

About the Author

Kate is a paediatric physiotherapist at NAPA Centre Sydney. Kate knows that a little bit of fun and laughter is the key to getting the job done. After seeing the benefits of intensive therapy firsthand, Kate is excited to help make a difference in the lives of NAPA kids and their families.

About NAPA Centre 

NAPA Centre provides paediatric therapy services to children diagnosed with Corpus Callosum. Learn more about treatment options in this blog post.NAPA specialises in working with children with physical and neurological delays. In addition to working with children with more common diagnoses such as cerebral palsy and Down syndrome, NAPA has a special interest and expertise with children with rare, multiple and complex conditions. NAPA Centre’s Intensive Model of Therapy (IMOT) is world-renowned, and one of the leading clinics in Australia for paediatric therapy programs with a large multi-discliplinary team of Occupational Therapists, Physiotherapists and Speech Therapists all working together. Families routinely travel from all parts of Sydney, the NSW region, from across Australia and even from the Australasian region to access NAPA’s unique and effective programs for their children.

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